Research Article
Association of Interleukin-6 Gene Promoter Polymorphism with Coronary Artery Disease in Pakistani Families
Table 1
Baseline and clinical characteristics of study population
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| Parameters | Patients () | Control () | value |
| Age (years) | | | 0.0050a | BMI (kg/m2) | | | 0.2755a | Female/male () | 16 (44.4%)/20 (55.6%) | 22 (42.3%)/30 (57.7%) | 0.8423b | Smokers/nonsmokers () | 8 (22.2%)/28 (77.8%) | 5 (9.6%)/47 (90.4%) | 0.1825b | SES (low/high) () | 23 (63.9%)/13 (36.1%) | 31 (60%)/21 (40%) | 0.8555b | Activity (low/high) () | 21 (58.3%)/15 (41.7%) | 9 (17.3%)/43 (82.7%) | 0.0002b | Stressed/nonstressed () | 27 (75%)/9 (25%) | 16 (30.8%)/36 (69.2%) | 0.0001b | Hypertensive/nonhypertensive () | 22 (61.1%)/14 (38.9%) | 7 (13.5%)/45 (86.5%) | <0.0001b | Systolic blood pressure () | | | <0.0001a | Diastolic blood pressure () | | | <0.0001a | Total-cholesterol (mg/dL) | | | 0.0035a | Triglycerides (mg/dL) | | | 0.0257a | LDL-cholesterol (mg/dL) | | | 0.0295a | HDL-cholesterol (mg/dL) | | | 0.0012a | Serum IL-6 (ng/dL) | | | 0.0268a | Serum hsCRP (mg/L) | | | <0.0001 |
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Values are given as means ± SD.
a values were calculated by using the Mann-Whitney test.
b values were calculated by the Pearson chi-square test.
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