Alignment of human SAT1 amino acid variants across species.
Species, accession number
% Identity to human SAT1
Human SAT1 variants
aM132T
R372H
Q556R
Human
100
M
R
Q
Chimpanzee, XM_003310211.1
98
M
R
R
Pygmy chimpanzee, XM_003811300.1
98
M
R
R
Sumatran orangutan, XM_002814495.1
96
M
R
R
Northern white-cheeked gibbon, XM_003280551.1
96
M
R
R
Olive baboon, XM_003890923.1
95
M
R
R
Rhesus monkey, XM_001093208.2
94
M
C
R
Bolivian squirrel monkey, XM_003934620.1
93
M
R
R
Dog, XM_545984.4
80
M
R
R
Cattle, XM_002688445.1
79
M
R
Q
Rat, CH474079.2
78
M
S
R
Mouse, BC025824.1
78
M
S
R
African clawed frog, NM_001090973.1
51
M
E
K
Rainbow trout, NM_001124486.1
50
M
R
K
Japanese eel, AB111927.1
49
M
R
K
Zebra fish, NM_001080667.1
48
M
R
K
Human SAT1 variants detected in this study are shown at the top, and the aligned amino acid for each species is shown below. Alignments were generated using the Clustal W program [11]. aIdentical amino acid across species.