Amelioration of Behavioural, Biochemical, and Neurophysiological Deficits by Combination of Monosodium Glutamate with Resveratrol/Alpha-Lipoic Acid/Coenzyme Q10 in Rat Model of Cisplatin-Induced Peripheral Neuropathy

Table 1

Effect of chronic treatment with combination of MSG and resveratrol/ALA/Co Q10 on levels of MDA (a marker of lipid peroxidation), reduced glutathion, and catalase in sciatic nerve of cisplatin treated rats.

SL. NO	Group	MDA; (µM/mg protein)	GSH; (µg/mg protein)	Catalase; (U/mg protein)
1	Vehicle	1.52±0.09	70.34±0.33	0.106±0.010
2	Cisplatin	2.76±0.19^∗∗∗	57.66±0.69^∗∗∗	0.051±0.004^∗∗∗
3	Cisplatin + MSG + Res	2.12±0.08^##	61.72±1.19^##	0.091±0.006^##
4	Cisplatin + MSG + Co Q10	2.22±0.04^#	60.63±0.47^#	0.088±0.008^#
5	Cisplatin + MSG + ALA	2.32±0.02^#	60.76±0.49^#	0.095±0.010^##

∗∗∗(𝑃<0.001) versus control group, ^#(𝑃<0.05), ^##(𝑃<0.01) versus cisplatin treated group.