Review Article

Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers

Table 1

Detected saliva levels (ng/mL) of nitrosamines such as MNPN, NGL, and NGC in chewers with tobacco and without tobacco.

BQ-specific N-nitrosaminesBQ alone (without tobacco)BQ + tobaccoReferences

MNPN0.5–11.4aProkopczyk et al., 1987 [36]
NGL0–5.90–7.1Nair et al., 1985 [38]
0.6–8.83.1–23.5Nair et al., 1987 [39]
2.2–9.5b4.3–45bWenke et al., 1984 [40]
0–142 Stich, 1986 [41]
NGC0–26.60–30.4Nair et al., 1985 [38]

Adapted from [16].
BQ: betel quid.
aThe data not reported.
bIn ppb.