Research Article

Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina

Figure 3

Relative magnitudes of cell proliferation, differentiation, and death in embryonic chick and mouse retinas. The results of the experiments described in Figures 1 and 2 were normalized per retinal surface area and hour, as explained in Section 3.2. Graphs represent the relative magnitude of cell proliferation (blue lines: BrdU-positive cells), differentiation (red lines: Islet1/2-positive cells), and death (green lines: TUNEL-positive cells) in chick (a) and mouse (b) embryonic retinas. The alternative slashed line representing cell death in the mouse retina indicates the magnitude of this process after subtracting the TUNEL-positive nuclei associated to the optic fissure, which plays a role in morphogenesis.
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(a)
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(b)