Design, Development, and Optimization of Polymeric Based-Colonic Drug Delivery System of Naproxen

Table 4

Regression coefficient (𝑟²) values of drug release data calculated from various drug release kinetic models and 𝑛 value in accordance with Korsemeyer-Peppas.

Formulation code	Zero order	First order	Higuchi	Korsemeyer-Peppas
	𝑟^2	𝑟^2	𝑟^2	𝑟^2	𝑛
NF1	0.892	0.986	0.990	0.979	0.399
NF2	0.896	0.986	0.992	0.976	0.419
NF3	0.950	0.884	0.988	0.978	0.847
NF4	0.916	0.976	0.993	0.970	0.786
NF5	0.951	0.956	0.987	0.984	0.823
NF6	0.919	0.977	0.980	0.975	0.401
NF7	0.934	0.957	0.959	0.951	0.693
NF8	0.949	0.930	0.958	0.949	0.728
NF9	0.954	0.955	0.956	0.953	0.735