Genome-Wide Analysis of DNA Methylation in Human Amnion

Table 1

Clinical characteristics of the three subject groups studied by genome-wide DNA methylation profiling.

Parameter	TNL (𝑛=9)^1	TL (𝑛=9)^1	PTL (𝑛=6)^2
Gestational age (weeks)^3	39.1 ± 0.8	38.8 ± 0.8	33.5 ± 2.6
Race
White	4	3	3
Black	0	0	1
Other	5	6	2
Maternal age at delivery (years)^3	29.7 ± 5.5	27 ± 4.4	28.7 ± 3.5
	(Range 22–38)	(Range 20–33)	(Range 25–33)
Antibiotics during pregnancy or labor
Yes	6	1	5
No	3	7	0
Unknown	0	1	1
Birth weight (grams)^3	3508.3 ± 267.2	3354.1 ± 348.6	2102.2 ± 724.6
Infant gender
Female	6	4	2
Male	3	5	4

¹Examined both individually and as a pooled sample.
²Examined as a pooled sample.
³Data are presented as mean ± standard deviation (SD).
Abbreviations: TNL: term no labor; TL: term labor; PTL: preterm labor.