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The Scientific World Journal
Volume 2013, Article ID 685917, 14 pages
Research Article

A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis

1Neuropsychiatric Research Laboratory, Department of Clinical Medicine, Örebro University, 701 82 Örebro, Sweden
2Metabolic Engineering and Bioinformatics Program, Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece
3Laboratory of Biotechnology, School of Chemical Engineering, National Technical University of Athens, 15780 Athens, Greece

Received 2 November 2012; Accepted 27 November 2012

Academic Editors: N. S. T. Hirata, M. A. Kon, and K. Najarian

Copyright © 2013 Marianthi Logotheti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The lists of differentiated transcripts after comparing the gene expression of control and either of SZ or BD patients from each dataset are presented in supplementary tables 1-6. The lists include the Gene ID, the Gene Symbol, the Gene Title, the p-value and the fold change in natural and in log2 scale for each differentially expressed transcript.

The results of GO-analysis for each dataset are presented in supplementary tables 7-12. GOT p-value represents the hypergeometric test p-value score for each GO term. Enrichment represents the ratio of the number of times a GO term occurs in the examined DE gene list to the number of times this GO term exists in the list of the entire microarray (for each study, its respective Affymetrix platform). GO terms presented in italics, are the ones considered most interesting in our study.

Supplementary Table 13: Kegg pathways based analysis. The lists of significantly altered genes from each study were submitted to StRAnGER analysis, elucidating over-represented Kegg terms.

  1. Supplementary Tables