Release of Gentamicin and Vancomycin from Preformed Spacers in Infected Total Hip Arthroplasties: Measurement of Concentrations and Inhibitory Activity in Patients’ Drainage Fluids and Serum

Table 1

In vitro activity of gentamicin and vancomycin in combination against multiresistant clinical isolates.

Vancomycin + gentamicin
Strain	MIC (mg/L)
	Vancomycin	Gentamicin	FICI
S. aureus	2.5	10	0.15
S. epidermidis	2.5	3750	1.00
S. haemolyticus	1.25	3750	1.00
S. haemolyticus Methicillin-resistant	1.25	3750	1.00
S. epidermidis Methicillin-resistant	2.5	58.6	0.50
S. hominis Methicillin-resistant	1.25	15	1.02
E. coli	156.25	5.0	0.25
P. aeruginosa	1250	5.0	0.12