Clinical Study

Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients

Table 3

Baseline characteristics in patients with < median physical activity and ≥ median physical activity.

All patients ( )Physical activity (steps/day)P
< Median value ( )≥ Median value ( )

Age, years68 (62, 74)70 (64, 75)66 (61, 71)0.04
Gender, women58 (50.0%)26 (44.8%)32 (55.2%)0.3
Body mass index, kg/m220.9 (19.1, 23.3)20.3 (18.9, 24.2)21.1 (19.5, 22.8)0.7
Time on hemodialysis, months66.5 (34.3, 150.8)73.0 (34.3,147.0)65.5 (33.5, 164.8)0.9
Primary kidney disease, %0.6
 Diabetic nephropathy41 (35.3%)20 (34.5%)21 (36.2%)
 Glomerulonephritis40 (34.5%)19 (32.8%)21 (36.2%)
 Hypertension6 (5.2%)2 (3.4%)4 (6.9%)
 Polycystic renal disease5 (4.3%)4 (6.9%)1 (1.7%)
 Other nephropathies11 (9.5%)7 (12.1%)4 (6.9%)
 Unknown13 (11.2%)6 (10.3%)7 (12.1%)
Comorbid condition, %
 Presence of cardiac disease31 (26.7%)16 (27.6%)15 (25.9%)0.8
 Presence of diabetes mellitus57 (49.1%)32 (55.2%)25 (43.1%)0.2
 Comorbidity score6.0 (3.3, 8.0)6.0 (4.0, 8.0)6.0 (3.0, 7.0)0.5
Laboratory parameters
 Albumin, g/dL3.8 (3.6, 3.9)3.8 (3.6, 3.9)3.8 (3.6, 4.0)0.8
 Creatinine, mg/dL10.2 (8.9, 11.4)10.3 (8.7, 11.2)10.2 (9.0, 11.6)0.7
 Hemoglobin, g/dL11.1 (10.7, 11.9)11.1 (10.7, 11.7)11.2 (10.7, 11.9)0.7
 Hematocrit, %33.2 (31.9, 34.9)33.2 (31.5, 34.6)33.3 (32.0, 35.4)0.3
 Phosphorus, mg/dL5.0 (4.2, 5.7)5.1 (4.3, 5.7)5.0 (4.2, 5.6)0.4
 Calcium, mg/dL8.7 (8.4, 9.2)8.8 (8.5, 9.1)8.6 (8.4, 9.2)0.2
 Intact PTH, pg/mL104.0 (57.5, 184.0)127.0 (69.5, 208.5)85.5 (40.0, 165.8)0.04
 HDL-C, mg/dL41.0 (32.0, 52.5)37.0 (30.0, 47.0)47.0 (38.0, 57.0)0.001
 LDL-C, mg/dL88.0 (70.0, 108.5)84.0 (65.5, 103.5)91.5 (71.5, 115.0)0.1
 Triglycerides, mg/dL119.0 (82.0, 159.5)136.0 (92.5, 179.5)112.5 (69.0, 143.3)0.04
Medications, %
 ACEI6 (5.2%)3 (5.2%)3 (5.2%)1.0
 ARB58 (50.0%)34 (58.6%)24 (41.4%)0.06
 CCB52 (44.8)26 (44.8%)26 (44.8%)1.0
 Beta-blocker32 (27.6%)20 (34.5%)12 (20.7%)0.1
 Lipid-modifier12 (10.3%)6 (10.3%)6 (10.3%)1.0
Smoking, %0.7
 Current12 (10.3%)7 (12.1%)5 (8.6%)
 Past56 (48.3%)27 (46.6%)29 (50.0%)
Brinkman index60.0 (0.0, 600.0)225.0 (0.0, 787.5)40.0 (0.0, 600)0.5
Physical activity
 Number of steps3208 (1828, 4481)1833 (1185, 2382)4478 (3726, 6242)<0.001

Values are expressed as median (25th, 75th percentiles) or number (percentage) of patients.
Intact PTH: intact parathyroid hormone; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker.