Hepatitis C Virus Infection: Looking for Interferon Free Regimens

Table 1

Some classical of predictors of sustained viral response (SVR).

	Positive predictors for SVR
HCV-related factors	Genotypes 2 and 3
	Subgenotypes 1a and 2a
	Low pretreatment VL
	RVR, eRVR, EVR
Host-related factors	Young age
	Absence of advanced liver fibrosis
	Caucasians
	IL28B CC genotype
Treatment-related factors	No RBV dose reduction (dose>10.6 mg/kg per day)
	Good adherence

eRVR: extended rapid virological response (undetectable HCV RNA at treatment week 4 and week 12); EVR: early virological response (HCV RNA detectable at week 4 but undetectable at week 12, maintained up to the end of treatment); HCV: hepatitis C virus; IL28B: interleukin 28B; RBV: ribavirin; RVR: rapid virological response (absence of measurable HCV RNA at week 4 of treatment); VL: viral load.