Research Article
Evaluation of the Antibacterial and Antifungal Potential of Peltophorum africanum: Toxicological Effect on Human Chang Liver Cell Line
Table 2
Mechanism of antibiosis using MLC/MICindex of the extract against test organisms.
| | Test bacteria and yeast | Ethyl acetate extract (mg/mL) | Tetracycline (g/mL) | | MIC* | MLC* | MLC/MICindex | MIC | MBC* |
| | Helicobacter pylori (ATCC 43526) | 2.5 | 10 | 4 | ND* | ND | | Pseudomonas aeruginosa (ATCC 15442) | 0.625 | 1.25 | 2 | ND | ND | | Plesiomonas shigelloides (ATCC 51903) | 0.15625 | 0.3125 | 2 | 10 | >10 | | Streptococcus pyogenes (ATCC 49399) | 0.625 | 2.5 | 4 | ND | ND | | Aeromonas hydrophila (ATCC 35654) | 2.5 | 5 | 2 | 10 | >10 | | Staphylococcus aureus (NCTC 6571) | 2.5 | 5 | 2 | >10 | >10 | | Shigella sonnei (ATCC 29930) | 1.25 | 5 | 4 | ND | ND | | Salmonella Typhimurium (ATCC 13311) | 1.25 | 2.5 | 2 | ND | ND | | Candida albicans (ATCC 2091) | 5 | >10 | >2 | 10 | >10 | | Cryptococcus neoformans (ATCC 66031) | 10 | ND | ND | ND | ND |
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: minimum inhibitory concentration; MLC: minimum lethal concentration; MBC: minimum bactericidal concentration; ND: not determined.
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