The Scientific World Journal

Research Article

Evaluation of the Antibacterial and Antifungal Potential of Peltophorum africanum: Toxicological Effect on Human Chang Liver Cell Line

Table 5

Inhibitory concentration (IC₅₀ & ₉₀) of the eight isolated bioactive fractions (mg/mL).


Bacteria/yeast	T1	T2	TEt1	TEt9	TEt10	BEtA2	BEtA3	BEtA4

A. hydrophila
IC₅₀	0.391	3.125	3.125	1.563	1.563	1.563	1.563	1.563
IC₉₀	1.563	ND*	ND	3.125	3.125	3.125	3.125	3.125
H. pylori
IC₅₀	6.25	3.125	6.25	3.125	6.25	1.563	ND	1.563
IC₉₀	ND	ND	ND	ND	ND	3.125	ND	3.125
P. aeruginosa
IC₅₀	1.563	3.125	3.125	3.125	1.563	0.781	1.563	0.024
IC₉₀	ND	ND	ND	ND	6.25	1.563	3.125	0.097
P. shigelloides
IC₅₀	1.563	3.125	3.125	3.125	3.125	1.563	1.563	0.781
IC₉₀	3.125	ND	ND	ND	ND	3.125	6.25	1.563
S. aureus
IC₅₀	0.781	3.125	3.125	1.563	1.563	0.781	0.781	0.781
IC₉₀	1.563	6.25	6.25	3.125	3.125	3.125	1.563	6.25
S. pyogenes
IC₅₀	0.781	3.125	1.563	3.125	3.125	0.781	1.563	0.391
IC₉₀	3.125	ND	6.25	ND	ND	1.563	3.125	1.563
S. sonnei
IC₅₀	0.781	3.125	3.125	1.563	1.563	0.391	1.563	1.563
IC₉₀	1.563	ND	ND	3.125	ND	1.563	3.125	6.25
S. Typhimurium
IC₅₀	0.391	3.125	3.125	1.563	3.125	0.781	3.125	1.563
IC₉₀	1.563	ND	ND	3.125	ND	3.125	6.25	1.563
C. albicans
IC₅₀	1.563	3.125	ND	0.781	1.563	0.781	0.781	0.391
IC₉₀	ND	6.25	ND	6.25	ND	1.563	1.563	1.563
C. neoformans
IC₅₀	1.563	3.125	6.25	1.563	ND	1.563	3.125	1.563
IC₉₀	ND	ND	ND	3.125	ND	3.125	6.25	6.25

IC₅₀
IC₉₀

: not determined.