Research Article
Evaluation of Allele Frequency Estimation Using Pooled Sequencing Data Simulation
Table 2
Statistics for doing 10,000 simulations at different MAFs.
| MAF | Min. | 1st Qu. | Median | Mean | 3rd Qu. | Max. | Var. | Relative RMSE |
| 0.5 | 0.0000 | 0.0036 | 0.0049 | 0.0050 | 0.0064 | 0.0162 | 0.0000 | 0.5037 | 1 | 0.0000 | 0.0075 | 0.0098 | 0.0100 | 0.0124 | 0.0264 | 0.0000 | 0.3552 | 5 | 0.0256 | 0.0448 | 0.0500 | 0.0500 | 0.0551 | 0.0795 | 0.0001 | 0.1540 | 10 | 0.0615 | 0.0928 | 0.0999 | 0.1000 | 0.1071 | 0.1401 | 0.0001 | 0.1070 | 20 | 0.1444 | 0.1904 | 0.2000 | 0.2001 | 0.2098 | 0.2558 | 0.0002 | 0.0716 | 30 | 0.2449 | 0.2889 | 0.2997 | 0.2998 | 0.3106 | 0.3619 | 0.0003 | 0.0537 | 40 | 0.3397 | 0.3879 | 0.3998 | 0.4000 | 0.4118 | 0.4707 | 0.0003 | 0.0442 | 50 | 0.4348 | 0.4877 | 0.5000 | 0.4998 | 0.5116 | 0.5675 | 0.0003 | 0.0359 |
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