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The Scientific World Journal
Volume 2013, Article ID 901215, 5 pages
Clinical Study

Increased Risk of Atrial and Ventricular Arrhythmia in Long-Lasting Psoriasis Patients

1Cardiology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, Turkey
2Van High Edücation and Research Hospital, 65100 Van, Turkey
3Dermatology Department, Faculty of Medicine, Yuzunci Yil University, 65200 Van, Turkey
4Cardiology Department, Hisar Intercontinental Hospital, 34768 Istanbul, Turkey

Received 25 January 2013; Accepted 3 March 2013

Academic Editors: C. Carbucicchio, H. Kitabata, A. N. Makaryus, C. Spaulding, and G. Stabile

Copyright © 2013 Hakki Simsek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Several reports have demonstrated an association between psoriasis and cardiovascular diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess homogeneity of cardiac repolarization and may be a risk for ventricular arrhythmias. Aim. To search PWD and QTD in patients with psoriasis. Methods. Ninety-four outpatient psoriasis patients and 51 healthy people were evaluated by physical examination, 12-lead ECG, and transthoracic echocardiography. Severity of the psoriasis was evaluated by psoriasis area and severity index (PASI). Results. Mean disease duration was (range, 3–360) months and PASI ranged from 0 to 34.0 (mean ± SD; ). Compared to control group, psoriatic patients had significantly shorter Pmax and Pmin durations, longer QTcmax, and greater PWD and QTcD. Transmitral deceleration time (DT) and isovolumetric relaxation time (IVRT) were significantly longer among psoriasis patients. QTcD and PWD were significantly correlated with disease duration ( , , and , , resp.). Conclusions. In this study, we found that both PWD and QTcD are increased in psoriasis patients compared to healthy subjects. In addition, they had longer DT and IVRT.