Research Article

Dengue Virus Type 2: Protein Binding and Active Replication in Human Central Nervous System Cells

Figure 2

Coimmunoprecipitation of central nervous system (CNS) proteins with dengue E viral protein. Coimmunoprecipitation assays revealed that four CNS proteins consistently bound with dengue virus particles. One major protein with molecular weight of 32 kDa and other two minor proteins with molecular weights of 100 and 130 kDa were obtained. These were not present in the control with no virus. Black arrows point to CNS protein bands that bound dengue virus E protein. *Protein bands with a minor signal.
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