MicroRNAs in Hepatocellular Carcinoma: Regulation, Function, and Clinical Implications

Table 2

SNPs in miRNAs and their target genes and the association with risk of HCC.

	Polymorphisms ID	Gene	Association with HCC Risk
Polymorphisms in miRNA genes	rs3859501	miR-371-373	Negative [157]
	rs7536540	miR-101-1	Positive [158]
	rs12375841	miR-101-2	Positive [158]
	rs2292832	miR-149c	Negative [159]
	rs3746444	miR-499a	No association [160]; Negative [159]; Positive [161]
	rs4938723	miR-34b/c	Positive [162]
	rs11614913	miR-196a-2	Positive [163–165]; No association [159]
	rs2910164	miR-146a	No association [159, 166]
	rs999885	miR-106b-25 cluster	Positive [167]
Polymorphisms in miRNA target genes	rs3783553	IL-1alpha	Positive [168]
	rs16405	betaTrCP	Positive [169]
	rs17875871	IFNAR1	Positive [170]
	rs6147150	ErbB4	Positive [171]
	rs3917	COL1A2	Positive [172]