The Scientific World Journal / 2013 / Article / Fig 4

Research Article

The Acetone Extract of Sclerocarya birrea (Anacardiaceae) Possesses Antiproliferative and Apoptotic Potential against Human Breast Cancer Cell Lines (MCF-7)

Figure 4

Effect of S. birrea acetone extract on MCF-7 cells at 24 h and subjected to acridine orange (Life technology, South Africa) and propidium iodide staining. (a) Negative control of untreated cells depicting viable cells (green nucleus), (b) cells treated with positive control curcumin (60 μM), showing late apoptosis (thick arrow), (c) treated cells with IC50 (87.6 μg/mL) concentration indicating early apoptosis (thin arrow), and (d) treated cells with IC50  ×  4 showing late apoptosis and secondary necrosis.