Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2013, Article ID 956206, 7 pages
http://dx.doi.org/10.1155/2013/956206
Research Article

The Acetone Extract of Sclerocarya birrea (Anacardiaceae) Possesses Antiproliferative and Apoptotic Potential against Human Breast Cancer Cell Lines (MCF-7)

1Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Fort Hare, P/Bag X1314, Alice 5700, South Africa
2Department of Microbiology and Parasitology, Faculty of Science, University of Buea, P.O. Box 63, Buea, Cameroon

Received 25 January 2013; Accepted 22 February 2013

Academic Editors: J.-T. Cheng, S. Cuzzocrea, and T. Hatano

Copyright © 2013 Nicoline Fri Tanih and Roland Ndip Ndip. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. I. Bieche, “Biologie moléculaire des cancers,” Immuno-Analyse & Biologie, vol. 19, pp. 13–22, 2004. View at Google Scholar
  2. A. T. Mbaveng, V. Kuete, B. M. Mapunya et al., “Evaluation of four Cameroonian medicinal plants for anticancer, antigonorrheal and antireverse transcriptase activities,” Environmental Toxicology and Pharmacology, vol. 32, no. 2, pp. 162–167, 2011. View at Google Scholar
  3. A. Prashar, I. C. Locke, and C. S. Evans, “Cytotoxicity of lavender oil and its major components to human skin cells,” Cell Proliferation, vol. 37, no. 3, pp. 221–229, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. M. L. Tan, S. F. Sulaiman, N. Najimuddin, M. R. Samian, and T. S. T. Muhammad, “Methanolic extract of Pereskia bleo (Kunth) DC. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line,” Journal of Ethnopharmacology, vol. 96, no. 1-2, pp. 287–294, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. L. Hilakivi-Clarke, C. Wang, M. Kalil, R. Riggins, and R. G. Pestell, “Nutritional modulation of the cell cycle and breast cancer,” Endocrine-Related Cancer, vol. 11, no. 4, pp. 603–622, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. C. W. Critchlow and N. B. Kiviat, “HPV-related neoplasia in HIV infection. Proposed mechanisms for development of malignancy,” in AIDS-Related Cancers and Their Treatment, R. J. Biggar, E. G. Feigal, and A. M. Levine, Eds., pp. 209–217, 2000. View at Google Scholar
  7. H. De Vuyst, S. Steyaert, L. Van Renterghem et al., “Distribution of human papillomavirus in a family planning population in Nairobi, Kenya,” Sexually Transmitted Diseases, vol. 30, no. 2, pp. 137–142, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. V. Ramakrishnan, A. G. Reddy, A. R. Reddy, and C. Haritha, “Evaluation of iron-induced oxidative stress and its amelioration by certain herbs in broilers,” Toxicology International, vol. 18, no. 1, pp. 54–57, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Heinrich and P. Bremner, “Ethnobotany and ethnopharmacy—their role for anti-cancer drug development,” Current Drug Targets, vol. 7, no. 3, pp. 239–245, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. D. J. Newman and G. M. Cragg, “Natural products as sources of new drugs over the last 25 years,” Journal of Natural Products, vol. 70, no. 3, pp. 461–477, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. O. Ojewole, T. Mawoza, W. D. H. Chiwororo, and P. M. O. Owira, “Sclerocarya birrea (A. Rich) Hochst. [“Marula”] (Anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses,” Phytotherapy Research, vol. 24, no. 5, pp. 633–639, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. A. O. Ojewole, “Evaluation of the anti-inflammatory properties of Sclerocarya birrea (A. Rich.) Hochst. (family: Anacardiaceae) stem-bark extracts in rats,” Journal of Ethnopharmacology, vol. 85, no. 2-3, pp. 217–220, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. N. F. Tanih and R. N. Ndip, “Evaluation of the acetone and aqueous extracts of mature stem bark of Sclerocarya birrea for antioxidant and antimicrobial properties,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 834156, 7 pages, 2012. View at Publisher · View at Google Scholar
  14. A. R. Ndhlala, A. Kasiyamhuru, C. Mupure, K. Chitindingu, M. A. Benhura, and M. Muchuweti, “Phenolic composition of Flacourtia indica, Opuntia megacantha and Sclerocarya birrea,” Food Chemistry, vol. 103, no. 1, pp. 82–87, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. F. M. Balis, “Evolution of anticancer drug discovery and the role of cell-based screening,” Journal of the National Cancer Institute, vol. 94, no. 2, pp. 78–79, 2002. View at Google Scholar · View at Scopus
  16. W. H. Talib and A. M. Mahasneh, “Antiproliferative activity of plant extracts used against cancer in traditional medicine,” Scientia Pharmaceutica, vol. 78, no. 1, pp. 33–45, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Norizah, I. Zakiah, and W. N. Wan Zurinah, “An evaluation of the anticancer activity in Hopea odorata extracts,” Journal of Medicinal Plant Research, vol. 6, no. 8, pp. 1382–1388, 2012. View at Google Scholar
  18. B. Giessrigl, G. Yazici, M. Teichmann et al., “Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers,” International Journal of Oncology, vol. 40, no. 6, pp. 2063–2074, 2012. View at Google Scholar
  19. A. Scalbert, I. T. Johnson, and M. Saltmarsh, “Polyphenols: antioxidants and beyond,” The American Journal of Clinical Nutrition, vol. 81, no. 1, supplement, pp. 215S–217S, 2005. View at Google Scholar · View at Scopus
  20. C. Njume, A. J. Afolayan, and R. N. Ndip, “Aqueous and organic solvent-extracts of selected South African medicinal plants possess antimicrobial activity against drug-resistant strains of Helicobacter pylori: inhibitory and bactericidal potential,” International Journal of Molecular Science, vol. 12, pp. 5652–5665, 2011. View at Google Scholar
  21. A. Bustamam, S. Mohan, S. Ibrahim et al., “In vitro ultramorphological assessment of apoptosis on CEMss induced by linoleic acid-rich fraction from Typhonium flagelliforme tuber,” Evidence-based Complementary and Alternative Medicine, vol. 2011, Article ID 421894, 12 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. T. Wang, K. B. Hicks, and R. Moreau, “Antioxidant activity of phytosterols, oryzanol, and other phytosterol conjugates,” Journal of the American Oil Chemists' Society, vol. 79, no. 12, pp. 1201–1206, 2002. View at Google Scholar · View at Scopus
  23. D. Mantle, T. W. J. Lennard, and A. T. Pickering, “Therapeutic applications of medicinal plants in the treatment of breast cancer: a review of their pharmacology, efficacy and tolerability,” Adverse Drug Reactions and Toxicological Reviews, vol. 19, no. 3, pp. 223–240, 2000. View at Google Scholar · View at Scopus
  24. O. K. Leong, T. S. T. Muhammad, and S. F. Sulaiman, “Cytotoxic activities of Physalis minima L. Chloroform extract on human lung adenocarcinoma NCI-H23 cell lines by induction of apoptosis,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 185064, 10 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. W. G. Ko, T. H. Kang, S. J. Lee, Y. C. Kim, and B. H. Lee, “Effects of Luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells,” Phytotherapy Research, vol. 16, no. 3, pp. 295–298, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Saleem, M. Husheem, P. Härkönen, and K. Pihlaja, “Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit,” Journal of Ethnopharmacology, vol. 81, no. 3, pp. 327–336, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Njume, A. J. Afolayan, E. Green, and R. N. Ndip, “Volatile compounds in the stem bark of Sclerocarya birrea (Anacardiaceae) possess antimicrobial activity against drug-resistant strains of Helicobacter pylori,” International Journal of Antimicrobial Agents, vol. 38, no. 4, pp. 319–324, 2011. View at Google Scholar