Expression Profiling Using a cDNA Array and Immunohistochemistry for the Extracellular Matrix Genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in Colorectal Carcinoma Progression and Dissemination

Table 10

The distribution of expression levels per IHC of proteins corresponding to ITGB-5, ITGA-3, MMP-2, MMP9, and FN-1 ECM genes and EGFR, VEGF, KI-67, P53, and Bcl-2 molecules as per the degrees of high and low expression of CRC (𝑛=114).

Markers	Low expression	High expression
	𝑛 (%)	𝑛 (%)
FN-1	81 (71.1)	33 (28.9)
ITGA-3	55 (48.2)	59 (51.8)
ITGB-5	63 (55.3)	51 (44.7)
MMP-2	53 (46.5)	61 (53.5)
MMP-9	59 (51.8)	55 (48.2)
P53	46 (40.4)	68 (59.6)
Bcl-2	57 (50.0)	57 (50.0)
KI-67	49 (43.0)	65 (57.0)
EGFR	69 (60.5)	45 (39.5)
VEGF	55 (48.2)	59 (51.8)