Clinical Study
The Incidence and Predictors of Thromboembolic Events in Patients with Lung Cancer
Table 1
Prothrombotic mechanisms in tumors.
| | Proaggregation and procoagulant activity, increased platelet | | Acceleration of thrombin production, overproduction of tissue
Factor, and other procoagulant factors | | Cytokine production by tumor cells, production of TNF-1,
interleukin-11, and VEGF | | Direct interactions between tumor cells and the endothelium of
blood vessels (increased adhesiveness) | | Factors related to cancer treatment—surgery, radiotherapy,
chemotherapy, and antiangiogenic treatment | | | Increased immobilization, central venous catheters | |
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