Noncovalent Interactions of Tiopronin-Protected Gold Nanoparticles with DNA: Two Methods to Quantify Free Energy of Binding

Figure 1

(a) Plot of fluorescence intensity at 656 nm of Au@tiopronin versus [AuNPs], in the absence of DNA. (b) Fluorescence spectra of AuNPs/DNA system recorded for increasing concentrations of DNA in 5% of ethanol. [AuNPs] = 1.5×10⁻⁶ M; [DNA] = 0 M (bottom); [DNA] = 7×10⁻⁵ M (top).

(a)

(b)