Noncovalent Interactions of Tiopronin-Protected Gold Nanoparticles with DNA: Two Methods to Quantify Free Energy of Binding

Figure 3

(a) CD titration of AuNPs with DNA in water. [DNA] = 1×10⁻⁴ M. Curves from (i) to (xv) correspond to 0, 0.15, 0.29, 0.39, 0.58, 0.71, 1.00, 1.50, 2.00, and 4.00 𝜇M of AuNPs. (b) Plot of the molar ellipticity experimental data versus AuNPs concentrations. Symbols (•) are experimental data and line is the best fit using (2).

(a)

(b)