Noncovalent Interactions of Tiopronin-Protected Gold Nanoparticles with DNA: Two Methods to Quantify Free Energy of Binding

Figure 6

(a) Fluorescence titration (𝜆_em=458nm) of 1-PyCHO with DNA in the presence of Au@tiopronin nanoparticles. ([1-PyCHO] = 5×10⁻⁷ M; [AuNPs] = 6×10⁻⁷  M; [DNA] = 0–5×10⁻⁴ M, given in base pairs). (b) Fit of the data to Hildebrand-Benesi model.

(a)

(b)