Fragile Histidine Triad (FHIT) Suppresses Proliferation and Promotes Apoptosis in Cholangiocarcinoma Cells by Blocking PI3K-Akt Pathway

Figure 3

The expression of survivin, Bcl-2, and caspase-3 in QBC939 cells in each group after transfection or treatment with LY294002. (a) The mRNA expression of survivin, Bcl-2, and caspase-3 in each group, as assessed by RT-PCR. (b) Western blotting for survivin, Bcl-2, and caspase-3. (c) Quantification of the expression levels of survivin, Bcl-2, and caspase-3 in each group, presented in bar graphs as fold-increase. ^∗𝑃<0.05, ^∗∗𝑃<0.01.

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