Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2014, Article ID 186508, 13 pages
http://dx.doi.org/10.1155/2014/186508
Research Article

Comparative Analysis of Cardiovascular Development Related Genes in Stem Cells Isolated from Deciduous Pulp and Adipose Tissue

1Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Hygieia Innovation Sdn. Bhd (852106-M), Lot 1G-2G, Lanai Complex No. 2, Persiaran Seri Perdana, Precint 10, 62250 Putrajaya, Malaysia
3Departments of Restorative Dentistry, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 3 July 2014; Revised 20 October 2014; Accepted 3 November 2014; Published 7 December 2014

Academic Editor: Yunfeng Lin

Copyright © 2014 Zhang Xin Loo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Jessup, W. T. Abraham, D. E. Casey et al., “2009 focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation,” Circulation, vol. 119, no. 14, pp. 1977–2016, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Sun, M. Cui, Z. Wang et al., “Mesenchymal stem cells modified with angiopoietin-1 improve remodeling in a rat model of acute myocardial infarction,” Biochemical and Biophysical Research Communications, vol. 357, no. 3, pp. 779–784, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Leor, N. Landa, and S. Cohen, “Renovation of the injured heart with myocardial tissue engineering,” Expert Review of Cardiovascular Therapy, vol. 4, no. 2, pp. 239–252, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Simonsson and Y. R. Bogestl, “Stem cell reprogramming: Generation of patient-specific stem cells by somatic cell nuclear reprogramming,” Stem Cells, vol. 5, no. 4, pp. e117–e124, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. M. A. Laflamme, K. Y. Chen, A. V. Naumova et al., “Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts,” Nature Biotechnology, vol. 25, no. 9, pp. 1015–1024, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Fukuda, “Reprogramming of bone marrow mesenchymal stem cells into cardiomyocytes,” Comptes Rendus—Biologies, vol. 325, no. 10, pp. 1027–1038, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Bearzi, M. Rota, T. Hosoda et al., “Human cardiac stem cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 35, pp. 14068–14073, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. C. Bearzi, A. Leri, F. Lo Monaco et al., “Identification of a coronary vascular progenitor cell in the human heart,” Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 37, pp. 15885–15890, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. D. D'Amario, C. Fiorini, P. M. Campbell et al., “Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies,” Circulation Research, vol. 108, no. 7, pp. 857–861, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Bolli, A. R. Chugh, D. D'Amario et al., “Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial,” The Lancet, vol. 378, no. 9806, pp. 1847–1857, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Gandia, A. N. A. Armiñan, J. M. García-Verdugo et al., “Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction,” Stem Cells, vol. 26, no. 3, pp. 638–645, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Cai, B. H. Johnstone, T. G. Cook et al., “IFATS collection: human adipose tissue-derived stem cells induce angiogenesis and nerve sprouting following myocardial infarction, in conjunction with potent preservation of cardiac function,” Stem Cells, vol. 27, no. 1, pp. 230–237, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. A. G. S. Lumsden, “Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ,” Development, vol. 103, pp. 155–169, 1988. View at Google Scholar · View at Scopus
  14. X. Cai, Y. Lin, P. V. Hauschka, and B. E. Grottkau, “Adipose stem cells originate from perivascular cells,” Biology of the Cell, vol. 103, no. 9, pp. 435–447, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. K. E. Hedin, J. A. Kaczynski, M. R. Gibson, and R. Urrutia, “Transcription factors in cell biology, surgery, and transplantation,” Surgery, vol. 128, no. 1, pp. 1–5, 2000. View at Publisher · View at Google Scholar · View at Scopus
  16. A. A. Filipczyk, R. Passier, A. Rochat, and C. L. Mummery, “Regulation of cardiomyocyte differentiation of embryonic stem cells by extracellular signalling,” Cellular and Molecular Life Sciences, vol. 64, no. 6, pp. 704–718, 2007. View at Google Scholar
  17. M. Ieda, J. D. Fu, P. Delgado-Olguin et al., “Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors,” Cell, vol. 142, no. 3, pp. 375–386, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. V. Govindasamy, A. N. Abdullah, V. S. Ronald et al., “Inherent differential propensity of dental pulp stem cells derived from human deciduous and permanent teeth,” Journal of Endodontics, vol. 36, no. 9, pp. 1504–1515, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. N. H. Abu Kasim, V. Govindasamy, N. Gnanasegaran et al., “Unique molecular signatures influencing the biological function and fate of post-natal stem cells isolated from different sources,” Journal of Tissue Engineering and Regenerative Medicine, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. V. Govindasamy, V. S. Ronald, S. Totey et al., “Micromanipulation of culture niche permits long-term expansion of dental pulp stem cells-an economic and commercial angle,” In Vitro Cellular and Developmental Biology—Animal, vol. 46, no. 9, pp. 764–773, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. D. M. Clifford, S. A. Fisher, S. J. Brunskill et al., “Stem cell treatment for acute myocardial infarction,” Cochrane Database of Systematic Reviews, no. 2, Article ID CD006536, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. M. F. Pittenger, A. M. Mackay, S. C. Beck et al., “Multilineage potential of adult human mesenchymal stem cells,” Science, vol. 284, no. 5411, pp. 143–147, 1999. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Dominici, K. Le Blanc, I. Mueller et al., “Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement,” Cytotherapy, vol. 8, no. 4, pp. 315–317, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Nakamura, Y. Yamada, W. Katagiri, T. Sugito, K. Ito, and M. Ueda, “Stem cell proliferation pathways comparison between human exfoliated deciduous teeth and dental pulp stem cells by genes expression profile from promising dental pulp,” Journal of Endodontics, vol. 35, no. 11, pp. 1536–1542, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Haack-Sørensen, S. K. Hansen, L. Hansen et al., “Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion,” Stem Cell Reviews and Reports, vol. 9, no. 1, pp. 44–58, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. L. Liu, X. Wei, J. Ling, L. Wu, and Y. Xiao, “Expression pattern of Oct-4, sox2, and c-Myc in the primary culture of human dental pulp derived cells,” Journal of Endodontics, vol. 37, no. 4, pp. 466–472, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Gesta, M. Blühet, Y. Yamamoto et al., “Evidence for a role of developmental genes in the origin of obesity and body fat distribution,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 17, pp. 6676–6681, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. I. Kerkis, A. Kerkis, D. Dozortsev et al., “Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers,” Cells Tissues Organs, vol. 184, no. 3-4, pp. 105–116, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. A. M. Aranha, Z. Zhang, K. G. Neiva, C. A. Costa, J. Hebling, and J. E. Nör, “Hypoxia enhances the angiogenic potential of human dental pulp cells,” Journal of Endodontics, vol. 36, no. 10, pp. 1633–1637, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. S.-C. Hung, R. R. Pochampally, S.-C. Chen, S.-C. Hsu, and D. J. Prockop, “Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis,” Stem Cells, vol. 25, no. 9, pp. 2363–2370, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Xin, C. A. Davis, J. D. Molkentin et al., “A threshold of GATA4 and GATA6 expression is required for cardiovascular development,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 30, pp. 11189–11194, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. R. Zhao, A. J. Watt, M. A. Battle, J. Li, B. J. Bondow, and S. A. Duncan, “Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice,” Developmental Biology, vol. 317, no. 2, pp. 614–619, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Bayes-Genis, C. Gálvez-Montón, C. Prat-Vidal, and C. Soler-Botija, “Cardiac adipose tissue: a new frontier for cardiac regeneration?” International Journal of Cardiology, vol. 167, no. 1, pp. 22–25, 2013. View at Publisher · View at Google Scholar · View at Scopus
  34. Y. S. Choi, G. J. Dusting, S. Stubbs et al., “Differentiation of human adipose-derived stem cells into beating cardiomyocytes,” Journal of Cellular and Molecular Medicine, vol. 14, no. 4, pp. 878–889, 2010. View at Publisher · View at Google Scholar · View at Scopus
  35. F. Ferro, R. Spelat, F. D'Aurizio et al., “Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics,” PLoS ONE, vol. 7, no. 7, Article ID e41774, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. E. Hoxha, E. Lambers, J. A. Wasserstrom et al., “Elucidation of a novel pathway through which HDAC1 controls cardiomyocyte differentiation through expression of SOX-17 and BMP2,” PLoS ONE, vol. 7, no. 9, Article ID e45046, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. S. J. Kattman, A. D. Witty, M. Gagliardi et al., “Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines,” Cell Stem Cell, vol. 8, no. 2, pp. 228–240, 2011. View at Publisher · View at Google Scholar · View at Scopus