2-Pentanone Production from Hexanoic Acid by Penicillium roqueforti from Blue Cheese: Is This the Pathway Used in Humans?

Table 2

(a) Ratio of the molecular ions (88/86) of 2-pentanone produced in paired vials during incubation with ¹H-hexanoic acid under ¹⁸O₂/¹⁴N₂ (88) and air (86). (b) Ratio of the molecular ions (97/95) of deuterated 2-pentanone produced in paired vials during incubation with hexanoic-D₁₁ acid under ¹⁸O₂/¹⁴N₂ (97) and air (95).

(a)

Paired vials	Ratio of 88/86 ions in ^18O2/^14N2 incubates	Ratio of 88/86 ions in air incubates
1	0.0066	0.0035
2	0.0066	0.0021
3	0.0076	0.0017
4	0.0041	0.0031
5	0.0063	0.0029
6	0.0100	0.0013
7	0.0092	0.0015

𝑃=0.0031; paired 𝑡-test.

(b)

Paired vials	Ratio of 97/95 ions in ^18O2/^14N2 incubates	Ratio of 97/95 ions in air incubates
1	0.0069	0.0034
2	0.0043	97 ions not detected
3	0.0050	97 ions not detected