Pharmacological Correction of Stress-Induced Gastric Ulceration by Novel Small-Molecule Agents with Antioxidant Profile

Table 1

Influence of compounds 3 (group VI) and 4 (group VII) (1 mg/kg, IP, 30 min before WIRS) on the content of lipid peroxidation products in homogenates of rats gastric mucosa (𝑛=6, M ± m).

Animals group	I	II	III	VI	VII
Conjugated dienes; (nmol mg protein^−1)	326.11 ± 25.78	518.33 ± 26.72**	465.56 ± 14.67**	443.89 ± 15.44^**#	352.22 ± 27.17^##
TBA-reactive substances; (nmol mg protein^−1)	69.4 ± 9.24	165.70 ± 12.25**	130.10 ± 10.26**	89.73 ± 6.55^##	98.26 ± 8.87^##
Schiff bases; (units mg protein^−1)	61.45 ± 4.68	97.53 ± 6.38**	92.17 ± 7.20**	75.17 ± 3.24^#	90.67 ± 4.52*

^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to the intact control group I; ^#𝑃<0.05, ^##𝑃<0.01 compared to the stress control group II.