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The Scientific World Journal
Volume 2014, Article ID 231293, 10 pages
http://dx.doi.org/10.1155/2014/231293
Research Article

Determination of Platycodin D and Platycodin D3 in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry

1Bioresourres Regional Innovation Center, Soonchunhyang University, Asan 336-745, Republic of Korea
2Industry-Academy Cooperation Foundation, Soonchunhyang University, Asan 336-745, Republic of Korea
3Korea Institute of Toxicology, Korea Research Institute of Chemical Technology, Daejeon 305-343, Republic of Korea
4College of Pharmacy, Dankook University, Cheonan 330-714, Republic of Korea
5Department of Pharmacology, College of Medicine, Dankook University, Cheonan 330-714, Republic of Korea
6Dankook Translational Research Center, Dankook University, Cheonan 330-714, Republic of Korea

Received 31 August 2013; Accepted 7 November 2013; Published 30 January 2014

Academic Editors: C. M. Davis and F. S. Hall

Copyright © 2014 Tae-Hyun Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Jin-Jun Shan, Jia-Shuang Zou, Tong Xie, An Kang, Wei Zhou, Jian-ya Xu, Cun-Si Shen, Li-Na Du, Shou-Chuan Wang, and Liu-Qing Di, “Effects of Gancao on pharmacokinetic profiles of platycodin D and deapio-platycodin D in Jiegeng,” Journal of Ethnopharmacology, 2015. View at Publisher · View at Google Scholar
  • Yu Peng, Feng Zhang, Hongxun Tao, Wei Wang, Lianna Sun, Wansheng Chen, and Changhong Wang, “Simultaneous determination of multiple platycosides with a single reference standard in Platycodi Radix by high-performance liquid chromatography coup,” Journal Of Separation Science, vol. 38, no. 21, pp. 3712–3719, 2015. View at Publisher · View at Google Scholar
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  • Wei Zhang, Shi-Hui Qian, Da-Wei Qian, and Song-Lin Li, “Screening of Intestinal Bacterial Metabolites of Platycodin D Using Ultra-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry,” American Journal of Chinese Medicine, vol. 44, no. 4, pp. 817–833, 2016. View at Publisher · View at Google Scholar
  • Piyush Mehta, and Vividha Dhapte, “A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines,” New Journal of Science, vol. 2016, pp. 1–31, 2016. View at Publisher · View at Google Scholar
  • Mihwa Kwon, Hyeon-Kyeong Ji, Soo Hyeon Goo, So Jeong Nam, Yun Ju Kang, Eunyoung Lee, Kwang Hyeon Liu, Min-Koo Choi, and Im-Sook Song, “Involvement of intestinal efflux and metabolic instability in?the?pharmacokinetics of platycodin D in rats,” Drug Metabolism and Pharmacokinetics, 2017. View at Publisher · View at Google Scholar
  • Zhongyao Tang, Yuanyuan Hou, Xueyan Hu, Aina Liu, Leefong Yau, Tiantian Tong, Zhihong Jiang, and Gang Bai, “Metabolite identification and pharmacokinetic study of platycodi radix (Jiegeng) in vivo,” RSC Adv., vol. 7, no. 59, pp. 37459–37466, 2017. View at Publisher · View at Google Scholar