Cytotoxic Activities of Flavonoids from Centaurea scoparia

Table 1

¹H, ¹³C, and selected HMBC NMR data for compounds 1 and 𝟐^∗.

Position	Compound 1			Compound 2
	𝛿H (𝐽 in Hz)	𝛿C	HMBC	𝛿H (𝐽 in Hz)	𝛿C	HMBC
2		156.6			154.2
3		133. 7			141.2
4		178.2			173.7
5	7.51 (1H, 𝑑, 𝐽=8.9)	128.1	4, 7, 8a	7.55 (1H, 𝑑, 𝐽=8.9)	127.9	4, 7, 8a
6	6.95 (1H, 𝑑, 𝐽=8.9)	116.9	7, 8, 4a	6.97 (1H, 𝑑, 𝐽=8.9)	116.5	7, 8, 4a
7		158.6			158.2
8		108.4			107.7
8a		155.7			155.1
4a		118.9			117.8
1′		129.7			129.6
2′	7.11 (1H, 𝑑, 𝐽=1.8)	119.5	1′, 3′, 4′, 6′	7.13 (1H, 𝑑, 𝐽=1.8)	119.4	1′, 3′, 4′, 6′
3′		152.4			152.4
4′		149.7			149.9
5′	6.90 (1H, 𝑑, 𝐽=8.1)	123.1	1′, 3′, 4′, 6′	6.93 (1H, 𝑑, 𝐽=8.1)	123.2	1′, 3′, 4′, 6′
6′	7.01 (1H, 𝑑𝑑, 𝐽=8.1, 1.8)	121.2	1′, 5′	7.05 (1H, 𝑑𝑑, 𝐽=8.1, 1.8)	121.1	1′, 5′
2′′		79.6			78.3
3′′	3.95 (1H, 𝑑, 𝐽=4.8)	69.7	4′′, 8, Me^1-2′′, Me^2-2′′	3.81 (1H, 𝑑, 𝐽=4.8)	69.4	4′′, 8, Me^1-2′′, Me^2-2′′
4′′	6.55 (1H, 𝑑, 𝐽=4.8)	63.5	2′′, 3′′, 7, 8, 8a, CO of AcO-4′′	5.24 (1H, 𝑑, 𝐽=4.8)	59.3	2′′, 3′′, 7, 8, 8a
Me^1-2′′	1.42 (3H, s)	26.6	2′′, 3′′	1.41 (3H, s)	24.1	2′′, 3′′
Me^2-2′′	1.39 (3H, s)	21.5	2′′, 3′′	1.38 (3H, s)	21.2	2′′, 3′′
OAc-4′′	1.95 (3H, s)	171/20.7
D-Glu
1′′′	4.95 (1H, 𝑑, 𝐽=6.9)	102.4	3
2′′′	3.24 (𝑚)	74.8	3′′′
3′′′	3.05 (𝑚)	77.9	2′′′, 4′′′
4′′′	3.11 (𝑚)	70.1	3′′′, 5′′′
5′′′	3.22 (𝑚)	76.7	4′′′
6′′′	3.45 (2H, 𝑚)	61.3

∗Measured in DMSO-𝑑₆ at 500 MHz (¹H) and 125 MHz (¹³C).