Medium Optimization for the Production of Fibrinolytic Enzyme by Paenibacillus sp. IND8 Using Response Surface Methodology

Table 1

Experimental design and results of the 2⁵ fractorial design.

Run	Sucrose	Yeast extract	NaH2PO4	pH	Moisture	Response (Y)
1	−1	1	−1	1	1	1711
2	−1	−1	1	−1	1	2169
3	1	1	−1	1	−1	1931
4	1	1	1	−1	−1	2297
5	−1	1	1	−1	1	3413
6	−1	1	1	1	−1	1244
7	−1	−1	−1	−1	1	1867
8	1	−1	1	1	1	1995
9	1	1	1	1	−1	1976
10	−1	−1	−1	1	1	2873
11	1	−1	1	−1	−1	723
12	−1	1	−1	−1	−1	787
13	1	−1	−1	−1	1	2681
14	1	−1	−1	−1	−1	2315
15	−1	1	−1	1	−1	1400
16	1	−1	1	1	−1	1400
17	1	1	−1	1	1	3514
18	1	1	−1	−1	1	2086
19	−1	−1	1	1	1	2535
20	1	−1	−1	1	1	2251
21	1	−1	−1	1	−1	2910
22	1	1	−1	−1	−1	1171
23	−1	−1	1	1	−1	1345
24	−1	1	1	1	1	1940
25	1	−1	1	−1	1	3331
26	−1	−1	1	−1	−1	2535
27	−1	1	1	−1	−1	2544
28	−1	−1	−1	1	−1	1381
29	1	1	1	1	1	2123
30	−1	−1	−1	−1	−1	1894
31	−1	1	−1	−1	1	1995
32	1	1	1	−1	1	3768