Research Article
Medium Optimization for the Production of Fibrinolytic Enzyme by Paenibacillus sp. IND8 Using Response Surface Methodology
Table 4
Central composite designs matrix and results on the production of fibrinolytic enzymes.
| Run | Factor A | Factor B | Factor C | Response (Y) |
| 1 | 1 | −1 | −1 | 3398 | 2 | 1 | 1 | 1 | 4008 | 3 | 0 | 0 | 0 | 3450 | 4 | −1.682 | 0 | 0 | 2903 | 5 | 1.682 | 0 | 0 | 2661 | 6 | 0 | 0 | 0 | 3360 | 7 | −1 | 1 | 1 | 3335 | 8 | 0 | −1.682 | 0 | 3661 | 9 | 0 | 0 | 0 | 3808 | 10 | 0 | 0 | 1.682 | 4418 | 11 | 1 | 1 | −1 | 1513 | 12 | 0 | 0 | 0 | 3673 | 13 | −1 | −1 | −1 | 1520 | 14 | 0 | 0 | 0 | 3755 | 15 | 1 | −1 | 1 | 3829 | 16 | 0 | 0 | 0 | 4314 | 17 | −1 | −1 | 1 | 4241 | 18 | −1 | 1 | −1 | 450 | 19 | 0 | 1.682 | 0 | 1713 | 20 | 0 | 0 | −1.682 | 1957 |
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