Medium Optimization for the Production of Fibrinolytic Enzyme by Paenibacillus sp. IND8 Using Response Surface Methodology

Table 5

ANOVA for response surface quadratic model.

Source	Sum of squares	df	Mean square	𝐹 Value	𝑃 value
Model	2.109𝐸+007	9	2.344𝐸+006	10.74	0.0005 significant
A-sucrose	5.720𝐸+005	1	5.720𝐸+005	2.62	0.1365
B-NaH2PO4	3.545𝐸+006	1	5.545𝐸+006	16.25	0.0024
C-moisture	1.176𝐸+007	1	1.176𝐸+007	53.88	<0.0001
AB	9112.50	1	9112.50	0.042	0.8422
AC	8.978𝐸+005	1	8.978𝐸+005	4.11	0.0700
BC	6.205𝐸+005	1	6.205𝐸+005	2.84	0.1226
A^2	1.706𝐸+006	1	1.706𝐸+006	7.82	0.0189
B^2	2.055𝐸+006	1	2.055𝐸+006	9.42	0.0119
C^2	5.805𝐸+005	1	5.805𝐸+005	2.66	0.1339
Residual	2.182𝐸+006	10	2.182𝐸+005
Lack of fit	1.616𝐸+006	5	3.232𝐸+005	2.85	0.1373 not significant
Pure error	5.662𝐸+005	5	1.132𝐸+005
Cor total	2.328𝐸+007	19