Preparation and Evaluation of Novel In Situ Gels Containing Acyclovir for the Treatment of Oral Herpes Simplex Virus Infections

Table 6

Ex vivo release data of different formulations.

Time (min.)	%Release
	Ft1	Fg1	Ft4	Fg4	MC
15	25.209	22.203	17	16.584	8.234
30	35.645	32.549	24.625	27.125	20.963
45	49.48	45.489	39.641	39.648	31.839
60	67.457	62.626	53.982	52.637	46.71
75	78.393	75.279	68.892	64.135	52.45
90	89.742	87.993	83.891	80.453	69.45
120	97.638	97.729	90.678	87.825	75.85
180	97.892	97.773	95.365	90.135	83.95
360	97.845	97.715	95.632	93.899	95.87

Fg and Ft: formulation code and MC: marketed cream.