Research Article
Cyanuric Chloride as an Efficient Catalyst for the Synthesis of 2,3-Unsaturated O-Glycosides by Ferrier Rearrangement
Table 1
Reaction conditions optimisation for the synthesis of 3a.
| Entry | Catalyst/mmol | Solvent | Time/min | Yield/% |
| 1 | 0 | CH2Cl2 | 120 | Trace | 2 | 0.05 | CH2Cl2 | 60 | 79 | 3 | 0.10 | CH2Cl2 | 30 | 90 | 4 | 0.15 | CH2Cl2 | 30 | 89 | 5 | 0.20 | CH2Cl2 | 30 | 90 | 6 | 0.10 | CH3CN | 30 | 82 | 7 | 0.10 | Acetone | 30 | 80 | 8 | 0.10 | THF | 30 | 69 | 9 | 0.10 | Ethyl ether | 60 | 42 |
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