Research Article
Anticonvulsant Potential of Certain New (2E)-2-[1-Aryl-3-(1H-imidazol-1-yl)propylidene]-N-(aryl/H)hydrazinecarboxamides
Scheme 2
Synthetic route for preparation of the target compounds 6a–p. Reagents and conditions: (i) HN(CH3)2·HCl, , conc. HCl, ethanol, reflux, 2 hrs; (ii) imidazole, water, reflux, 5 hrs; (iii) appropriate semicarbazide 3a–f, ethanol, acetic acid, RT, 18 hrs or semicarbazide hydrochloride, anhydrous sodium acetate, ethanol, RT, 18 hrs for 6g and 6l.
