The Scientific World Journal / 2014 / Article / Sch 2

Research Article

Anticonvulsant Potential of Certain New (2E)-2-[1-Aryl-3-(1H-imidazol-1-yl)propylidene]-N-(aryl/H)hydrazinecarboxamides

Scheme 2

Synthetic route for preparation of the target compounds 6ap. Reagents and conditions: (i) HN(CH3)2·HCl, , conc. HCl, ethanol, reflux, 2 hrs; (ii) imidazole, water, reflux, 5 hrs; (iii) appropriate semicarbazide 3a–f, ethanol, acetic acid, RT, 18 hrs or semicarbazide hydrochloride, anhydrous sodium acetate, ethanol, RT, 18 hrs for 6g and 6l.
357403.sch.002

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