Prognostic Implication of Preoperative Behavior Changes in Patients with Primary High-Grade Meningiomas

Table 3

Univariate survival analysis of 86 high-grade meningiomas.

Variable	𝑛	Recurrence-free survival			Overall survival
		HR	95% CI	𝑃 value	HR	95% CI	𝑃 value
Sex (male versus female)	86	1.9	0.9–4.0	0.077	1.9	1.0–3.8	0.064
Age (≥55 versus <55)	86	0.9	0.5–1.8	0.776	3.19	1.5–6.7	0.002
Location (parasagittal-falcine versus others)	86	2.3	1.1–4.7	0.021	1.5	0.8–3.0	0.238
WHO Grade (III versus II)	86	2.0	0.8–5.3	0.145	1.7	0.6–4.3	0.293
Brain invasion (present versus absent)	37	7.2	0.9–55.7	0.059	4.4	1.0–19.2	0.049
Ki67 (>4% versus ≤4%)	86	2.7	1.1–6.7	0.027	1.9	0.9–4.0	0.104
Behavior changes (present versus absent)	83	0.7	0.3–1.7	0.514	1.0	0.5–2.0	0.112