Shedding Light on a New Treatment for Diabetic Wound Healing: A Review on Phototherapy
Figure 2
Laser light is absorbed by chromophores in the cell, mitochondria in the case of visible red light. This leads to an increase in adenosine triphosphate (ATP), reactive oxygen species (ROS), nitric oxide (NO), and intracellular calcium (iCa2+). There is an activation of transcription factors which get translocated to the nucleus and activate gene transcription. This leads to increased cell survival and wound healing.
