Research Article

Effect of Gamma Irradiation on Structural and Biological Properties of a PLGA-PEG-Hydroxyapatite Composite

Table 5

Detailed results of MTT assay (percent of vital cells in comparison to control group) for hydroxyapatite, copolymer, and composite under 0, 25, and 50 KGy doses of gamma irradiation in days 3, 7, and 14.

Material Nonirradiated samples
Percent of vital cells in comparison to control group
25 KGy irradiated samples
Percent of vital cells in comparison to control group
50 KGy irradiated samples
Percent of vital cells in comparison to control group
Day 3Day 7Day 14Day 3Day 7Day 14Day 3Day 7Day 14

Hydroxyapatite47.7 ± 4.66 40.79 ± 10.6639.43 ± 1.2364.3 ± 12.849.42 ± 7.0871 ± 15.247.28 ± 260.77 ± 3.5565.4 ± 12
Copolymer32.07 ± 2.0223.5 ± 5.5814.68 ± 0.5240.9 ± 217.87 ± 1.9815.07 ± 1.734.6 ± 4.5717.28 ± 2.4416.88 ± 2.7
Composite36.65 ± 0.821.44 ± 1.0724.34 ± 6.1353.26 ± 22.820.37 ± 4.0223.6 ± 4.338.26 ± 3.5224.61 ± 9.322.1 ± 6.2