Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation

Table 5

Solutions that meet the criteria required for floating pulsatile release tablets.

Batch number	PEO %	Coat weight	Lag time (h)	Release at 7 h (%)	Release at 12 h (%)	Desirability
1	20	480.77	6.00	75.71	101.81	0.795
2	40	300.00	4.38	74.15	105.20	0.751
3	40	306.71	4.52	78.76	103.71	0.741