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The Scientific World Journal
Volume 2014 (2014), Article ID 437081, 8 pages
http://dx.doi.org/10.1155/2014/437081
Research Article

In Vitro Study on the Antioxidant Potentials of the Leaves and Fruits of Nauclea latifolia

1Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Bellville 7535, South Africa
2Department of Wellness Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 8000, South Africa

Received 3 April 2014; Revised 13 May 2014; Accepted 19 May 2014; Published 11 June 2014

Academic Editor: Okezie I. Aruoma

Copyright © 2014 Ademola O. Ayeleso et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study was carried out to investigate the in vitro antioxidant potentials of the leaves and fruits of Nauclea latifolia, a straggling shrub or small tree, native to tropical Africa and Asia. Hot water extracts of the leaves and fruits of Nauclea latifolia were assessed for their total polyphenolic, flavanol, and flavonol contents as well as 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging ability, ferric reducing antioxidant power (FRAP), Trolox equivalence antioxidant capacity (TEAC), and oxygen radical absorbance capacity (ORAC) assays. The aqueous extract of the leaves was found to contain higher level of total polyphenols (  mg GAE/g), flavanol (  mg CE/g), and flavonol (  mg QE/g) than the extract of the fruits with values of  mg GAE/g (total polyphenol),  mg CE/g (flavanol), and  mg QE/g (flavonol). Similarly, the aqueous extract of the leaves also exhibited higher DPPH (IC50 20.64 mg/mL), FRAP ( μmol AAE/g), TEAC ( μmol TE/g), and ORAC ( μmol TE/g) than the extract of the fruits with DPPH (IC50 120.33 mg/mL), FRAP ( μmol AAE/g), TEAC ( μmol TE/g), and ORAC ( μmol TE/g). The present study showed that Nauclea latifolia has strong antioxidant potentials with the leaves demonstrating higher in vitro antioxidant activities than the fruits.