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The Scientific World Journal
Volume 2014, Article ID 437081, 8 pages
http://dx.doi.org/10.1155/2014/437081
Research Article

In Vitro Study on the Antioxidant Potentials of the Leaves and Fruits of Nauclea latifolia

1Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Bellville 7535, South Africa
2Department of Wellness Sciences, Faculty of Health & Wellness Sciences, Cape Peninsula University of Technology, Cape Town 8000, South Africa

Received 3 April 2014; Revised 13 May 2014; Accepted 19 May 2014; Published 11 June 2014

Academic Editor: Okezie I. Aruoma

Copyright © 2014 Ademola O. Ayeleso et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. krovánková, L. Mišurcová, and L. Machů, “Antioxidant activity and protecting health effects of common medicinal plants,” Advances in Food and Nutrition Research, vol. 67, pp. 75–139, 2012. View at Google Scholar
  2. N. A. Khalaf, A. K. Shakya, A. Al-Othman, Z. El-Agbar, and H. Farah, “Antioxidant activity of some common plants,” Turkish Journal of Biology, vol. 32, no. 1, pp. 51–55, 2008. View at Google Scholar · View at Scopus
  3. T. P. A. Devasagayam, J. C. Tilak, K. K. Boloor, K. S. Sane, S. S. Ghaskadbi, and R. D. Lele, “Free radicals and antioxidants in human health: current status and future prospects,” Journal of Association of Physicians of India, vol. 52, pp. 794–804, 2004. View at Google Scholar · View at Scopus
  4. O. James and H. H. Ugbede, “Hypocholesterolemic effects of Nauclea latifolia (Smith) fruit studied in albino rats,” American Journal of Tropical Medicine and Public Health, vol. 1, no. 1, pp. 11–21, 2011. View at Google Scholar
  5. S. D. Karou, T. Tchacondo, D. P. Ilboudo, and J. Simpore, “Sub-saharan rubiaceae: a review of their traditional uses, phytochemistry and biological activities,” Pakistan Journal of Biological Sciences, vol. 14, no. 3, pp. 149–169, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. I. I. Nkafamiya, A. J. Manji, U. U. Modibbo, and H. A. Umaru, “Biochemical evaluation of Cassipourea congoensis (Tunti) and Nuclea latifolia (Luzzi) fruits,” African Journal of Biotechnology, vol. 5, no. 24, pp. 2461–2463, 2006. View at Google Scholar · View at Scopus
  7. A. D. T. Goji, A. Mohammed, Y. Tanko, I. Ezekiel, A. O. Okpanchi, and A. U. U. Dikko, “A study of the anti-inflammatory and analgesic activities of aqueous extract of Nauclea latifolia leaves in Rodent,” Asian Journal of Medical Sciences, vol. 2, no. 6, pp. 244–247, 2010. View at Google Scholar
  8. A. Gidado, D. A. Ameh, and S. E. Atawodi, “Effect of Nauclea latifolia leaves aqueous extracts on blood glucose levels of normal and alloxan-induced diabetic rats,” African Journal of Biotechnology, vol. 4, no. 1, pp. 91–93, 2005. View at Google Scholar · View at Scopus
  9. A. Gidado, D. A. Ameh, S. E. Atawodi, and S. Ibrahim, “Hypoglycaemic activity of Nauclea latifolia sm. (Rubiaceae) in experimental animals,” African Journal of Traditional, Complementary and Alternative Medicines, vol. 5, no. 2, pp. 201–208, 2008. View at Google Scholar · View at Scopus
  10. O. N. Maitera, M. E. Khan, and T. F. James, “Phytochemical analysis and the chemotherapeutics of leaves and stem-bark of Nauclea latifolia grown in Hong, Adamawa State Nigeria,” Asian Journal of Plant Sciences, vol. 1, no. 3, pp. 16–22, 2011. View at Google Scholar
  11. F. Benoit-Vical, A. Valentin, V. Cournac, Y. Pélissier, M. Mallié, and J.-M. Bastide, “In vitro antiplasmodial activity of stem and root extracts of Nauclea latifolia S.M. (Rubiaceae),” Journal of Ethnopharmacology, vol. 61, no. 3, pp. 173–178, 1998. View at Publisher · View at Google Scholar · View at Scopus
  12. P. I. Akubue and G. C. Mittal, “Clinical evaluation of a traditional herbal practice in Nigeria: a preliminary report,” Journal of Ethnopharmacology, vol. 6, no. 3, pp. 355–359, 1982. View at Google Scholar · View at Scopus
  13. Z. A. M. Nworgu, D. N. Onwukaeme, A. J. Afolayan, F. C. Amaechina, and B. A. Ayinde, “Preliminary Studies of blood lowering effects of Nauclea latifolia in rats,” African Journal of Pharmacology, vol. 2, no. 2, pp. 37–41, 2008. View at Google Scholar
  14. F. V. Udoh and T. Y. Lot, “Effects of leaf and root extracts of Nauclea latifolia on the cardiovascular system,” Fitoterapia, vol. 69, no. 2, pp. 141–146, 1998. View at Google Scholar · View at Scopus
  15. G. S. Taïwe, E. N. Bum, E. Talla et al., “Antipyretic and antinociceptive effects of Nauclea latifolia root decoction and possible mechanisms of action,” Pharmaceutical Biology, vol. 49, no. 1, pp. 15–25, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. M. El-Mahmood, J. H. Doughari, and F. J. Chanji, “In vitro antibacterial activities of crude extracts of Nauclea latifolia and Daniella oliveri,” Scientific Research and Essays, vol. 3, no. 3, pp. 102–105, 2008. View at Google Scholar · View at Scopus
  17. W. Okiei, M. Ogunlesi, E. A. Osibote, M. K. Binutu, and M. A. Ademoye, “Comparative studies of the antimicrobial activity of components of different polarities from the leaves of Nauclea latifolia,” Research Journal of Medicinal Plant, vol. 5, no. 3, pp. 321–329, 2011. View at Google Scholar
  18. V. L. Singleton, R. Orthofer, and R. M. Lamuela-Raventós, “Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent,” Methods in Enzymology, vol. 299, pp. 152–178, 1998. View at Publisher · View at Google Scholar · View at Scopus
  19. J. A. Delcour and J. D. de Varebeke, “A new colorimetric assay for flavonoids in pilsner beers,” Journal of the Institute of Brewing, vol. 91, no. 1, pp. 37–40, 1985. View at Google Scholar
  20. D. Treutter, “Chemical reaction detection of catechins and proanthocyanidins with 4-dimethylaminocinnamaldehyde,” Journal of Chromatography A, vol. 467, pp. 185–193, 1989. View at Google Scholar · View at Scopus
  21. G. Mazza, L. Fukumoto, P. Delaquis, B. Girard, and B. Ewert, “Anthocyanins, phenolics, and color of Cabernet Franc, Merlot, and Pinot Noir wines from British Columbia,” Journal of Agricultural and Food Chemistry, vol. 47, no. 10, pp. 4009–4017, 1999. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Z. Zheleva-Dimitrova, “Antioxidant and acetylcholinesterase inhibition properties of Amorpha fruticosa L. and Phytolacca americana L,” Pharmacognosy Magazine, vol. 9, no. 34, pp. 109–113, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. I. F. F. Benzie and J. J. Strain, “The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay,” Analytical Biochemistry, vol. 239, no. 1, pp. 70–76, 1996. View at Publisher · View at Google Scholar · View at Scopus
  24. B. Ou, M. Hampsch-Woodill, and R. L. Prior, “Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe,” Journal of Agricultural and Food Chemistry, vol. 49, no. 10, pp. 4619–4626, 2001. View at Publisher · View at Google Scholar · View at Scopus
  25. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang, and C. Rice-Evans, “Antioxidant activity applying an improved ABTS radical cation decolorization assay,” Free Radical Biology and Medicine, vol. 26, no. 9-10, pp. 1231–1237, 1999. View at Publisher · View at Google Scholar · View at Scopus
  26. N. R. Farnsworth, “Screening plants for new medicine,” in Biodiversity, E. O. Wilson, Ed., Part II, pp. 88–97, National Academy Press, Washington, DC, USA, 1989. View at Google Scholar
  27. T. Eisner, “Chemical prospecting: a call for action,” in Ecology, Economic and Ethics: The Broken Circles, F. E. Borman and S. R. Kellert, Eds., Yale University Press, 1990. View at Google Scholar
  28. N. Saeed, M. R. Khan, and M. Shabbir, “Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L,” BMC Complementary and Alternative Medicine, vol. 12, article 221, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Anwar, A. Jamil, S. Iqbal, and M. A. Sheikh, “Antioxidant activity of various plant extracts under ambient and accelerated storage of sunflower oil,” Grasas y Aceites, vol. 57, no. 2, pp. 189–197, 2006. View at Google Scholar · View at Scopus
  30. T. Osawa, S. Kavakishi, M. Namiki, Y. Kuroda, D. M. Shankal, and M. D. Waters, Antimutagenesis and Anticarcinogenesis Mechanisms II, Plenum, New York, NY, USA, 1990.
  31. A. Karadag, B. Ozcelik, and S. Saner, “Review of methods to determine antioxidant capacities,” Food Analytical Methods, vol. 2, no. 1, pp. 41–60, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. M. P. Kähkönen, A. I. Hopia, H. J. Vuorela et al., “Antioxidant activity of plant extracts containing phenolic compounds,” Journal of Agricultural and Food Chemistry, vol. 47, no. 10, pp. 3954–3962, 1999. View at Publisher · View at Google Scholar · View at Scopus
  33. M. Suhaj, “Spice antioxidants isolation and their antiradical activity: a review,” Journal of Food Composition and Analysis, vol. 19, no. 6-7, pp. 531–537, 2006. View at Publisher · View at Google Scholar · View at Scopus
  34. M. Öztürk, F. Aydoǧmuş-Öztürk, M. E. Duru, and G. Topçu, “Antioxidant activity of stem and root extracts of Rhubarb (Rheum ribes): an edible medicinal plant,” Food Chemistry, vol. 103, no. 2, pp. 623–630, 2007. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Maizura, A. Aminah, and W. M. Wan Aida, “Total phenolic content and antioxidant activity of kesum, ginger (Zingiber officinale) and turmeric (Curcuma longa) extract,” International Food Research Journal, vol. 18, pp. 529–534, 2011. View at Google Scholar
  36. N. Gherraf, S. Ladjel, B. Labed, and S. Hameurlaine, “Evaluation of antioxidant potential of various extracts of Traganum nudatumdel,” Plant Sciences Feed, vol. 1, no. 9, pp. 155–159, 2011. View at Google Scholar
  37. K. Shukla, P. Dikshit, M. K. Tyagi, R. Shukla, and J. K. Gambhir, “Ameliorative effect of Withania coagulans on dyslipidemia and oxidative stress in nicotinamide-streptozotocin induced diabetes mellitus,” Food and Chemical Toxicology, vol. 50, no. 10, pp. 3595–3599, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. H. B. Niemeyer and M. Metzler, “Differences in the antioxidant activity of plant and mammalian lignans,” Journal of Food Engineering, vol. 56, no. 2-3, pp. 255–256, 2003. View at Publisher · View at Google Scholar · View at Scopus
  39. P.-J. Tsai, J. McIntosh, P. Pearce, B. Camden, and B. R. Jordan, “Anthocyanin and antioxidant capacity in Roselle (Hibiscus sabdariffa L.) extract,” Food Research International, vol. 35, no. 4, pp. 351–356, 2002. View at Publisher · View at Google Scholar · View at Scopus
  40. C. Priyanka, D. A. Kadam, A. S. Kadam, Y. A. Ghule, and V. T. Aparadh, “Free radical scavenging (DPPH) and ferric reducing ability (FRAP) of some gymnosperm species,” International Research Journal of Botany, vol. 3, no. 2, pp. 34–36, 2013. View at Google Scholar
  41. Y. Li, C. Guo, J. Yang, J. Wei, J. Xu, and S. Cheng, “Evaluation of antioxidant properties of pomegranate peel extract in comparison with pomegranate pulp extract,” Food Chemistry, vol. 96, no. 2, pp. 254–260, 2006. View at Publisher · View at Google Scholar · View at Scopus
  42. A. D. Gupta, V. Pundeer, G. Bande, S. Dhar, I. R. Ranganath, and G. S. Kumari, “Evaluation of antioxidant activity of four folk antidiabetic medicinal plants of India,” Pharmacologyonline, vol. 1, pp. 200–208, 2009. View at Google Scholar · View at Scopus
  43. A. L. Rice and J. B. Burns, “Moving from efficacy to effectiveness: red palm oil's role in preventing vitamin A deficiency,” Journal of the American College of Nutrition, vol. 29, no. 1, supplement, pp. 302S–313S, 2010. View at Google Scholar · View at Scopus
  44. L. Wang, S. Liu, A. D. Pradhan et al., “Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in women,” American Journal of Epidemiology, vol. 164, no. 6, pp. 576–585, 2006. View at Publisher · View at Google Scholar · View at Scopus
  45. H.-B. Li, C.-C. Wong, K.-W. Cheng, and F. Chen, “Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants,” LWT—Food Science and Technology, vol. 41, no. 3, pp. 385–390, 2008. View at Publisher · View at Google Scholar · View at Scopus
  46. C.-T. Yeh and G.-C. Yen, “Induction of hepatic antioxidant enzymes by phenolic acids in rats is accompanied by increased levels of multidrug resistance-associated protein 3 mRNA expression,” Journal of Nutrition, vol. 136, no. 1, pp. 11–15, 2006. View at Google Scholar · View at Scopus
  47. Y.-J. Cai, Q.-Y. Wei, J.-G. Fang et al., “The 3,4-dihydroxyl groups are important for trans-resveratrol analogs to exhibit enhanced antioxidant and apoptotic activities,” Anticancer Research, vol. 24, no. 2, pp. 999–1002, 2004. View at Google Scholar · View at Scopus
  48. L. Hou, B. Zhou, L. Yang, and Z.-L. Liu, “Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides,” Chemistry and Physics of Lipids, vol. 129, no. 2, pp. 209–219, 2004. View at Publisher · View at Google Scholar · View at Scopus
  49. L. Hou, B. Zhou, L. Yang, and Z.-L. Liu, “Inhibition of free radical initiated peroxidation of human erythrocyte ghosts by flavonols and their glycosides,” Organic and Biomolecular Chemistry, vol. 2, no. 9, pp. 1419–1423, 2004. View at Publisher · View at Google Scholar · View at Scopus
  50. A. A. Fadda, R. E. El-Mekawy, A. El-Shafei, H. S. Freeman, D. Hinks, and M. El-Fedawy, “Design, synthesis, and pharmacological screening of novel porphyrin derivatives,” Journal of Chemistry, vol. 2013, Article ID 340230, 11 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus