Research Article

NMDA Receptor-Mediated Neuroprotective Effect of the Scutellaria baicalensis Georgi Extract on the Excitotoxic Neuronal Cell Death in Primary Rat Cortical Cell Cultures

Figure 4

The ethanol extract of Scutellaria baicalensis inhibits the binding of [3H]MK-801 to the N-methyl-D-aspartate (NMDA) receptor. Different concentrations of the extract (here we used 10, 25, 50, and 100 μg/mL) were employed. Nonspecific binding determined in the presence of 200 μM MK-801 was subtracted from the total binding. Data were calculated as percent of the control binding measured in the absence of the extract. Each point represents the mean ± S.D. ; (compared with control binding).
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