Evaluation on Genotoxicity and Teratogenicity of Aqueous Extract from Cyclocarya paliurus Leaves

Table 6

Effect of C. paliurus leaf aqueous extract on the indexes of embryo toxicity in pregnant rat. Data are expressed as mean ± SD.

Groups/(g/kg·bw)

Numbers

Dead and adsorptive Incidence/(%)

Weight/(g)

Pregnant rat number

Corpora lutea

Nidation

Live embryo

Ovary

Uterus linking to Placenta

Placenta

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

𝑥  ±  𝑠

𝑃

Negative controls

12

13.3±2.3

0.905

11.8±2.1

0.690

11.6±2.1

/

1.42

/

0.186 ± 0.042

0.805

66.42±6.86

/

6.70±1.25

/

5.0

12

13.5±2.6

11.3±2.4

11.2±2.5

0.977

0.74

1.000

0.183 ± 0.039

63.34±9.73

0.789

6.95±0.92

0.970

10.0

12

13.6±1.8

11.7±2.3

11.4±2.3

0.999

2.14

0.684

0.194 ± 0.043

65.64±8.32

0.998

6.78±1.34

0.999

20.0

12

13.2±2.2

11.3±2.6

11.2±2.7

0.977

1.47

1.000

0.198 ± 0.046

64.80±10.25

0.973

6.56±1.66

0.997

Positive controls

12

12.8±2.1

10.5±2.0

7.8±1.9

0.001

25.4

0.000

0.179 ± 0.040

44.43±7.01

0.000

5.05±1.26

0.012