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The Scientific World Journal
Volume 2014, Article ID 538283, 5 pages
Clinical Study

The Anterior Chamber Depth and Retinal Nerve Fiber Layer Thickness in Children

Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong

Received 17 July 2014; Revised 15 October 2014; Accepted 15 October 2014; Published 9 November 2014

Academic Editor: Ahmad M. Mansour

Copyright © 2014 Jacky W. Y. Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To investigate the correlation of anterior chamber depth (ACD) with the peripapillary retinal nerve fiber layer (RNFL) thickness, age, axial length (AL), and spherical equivalent in children. Subjects. Consecutive subjects aged 4 to 18 were recruited. Visually disabling eye conditions were excluded. Only the right eye was included for analysis. The ACD was correlated with RNFL thickness, age, spherical equivalent, and AL for all subjects. Subjects were then divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<−1.0 D), emmetropes (≥−1.0 to ≤+1.0 D), and hyperopes (>+1.0 D). The ACD was compared among the 3 groups before and after age adjustment. Results. In 200 subjects (mean age years), a deeper ACD was correlated with thinner global RNFL (, , ), older age (, , ), myopic spherical equivalent (, , ), and longer AL (, , ). The ACD was deepest in myopes ( mm, ), followed by emmetropes (, ) and then hyperopes (, ) (all ). After age adjustment, myopes had a deeper ACD than the other 2 groups (all ). Conclusions. In children, a deeper ACD was associated with thinner RNFL thickness, older age, more myopic spherical equivalent, and longer AL. Myopes had a deeper ACD than emmetropes and hyperopes.