A Method for the Simultaneous Determination of Chlorogenic Acid and Sesquiterpene Lactone Content in Industrial Chicory Root Foodstuffs

Table 5

Recovery (%) of the extraction of H₂O/CHCl₃/MeOH 30/30/40 (v/v/v) with different additions (5-CQA, 3,5-diCQA, and DHLc) to flour.

	Metabolites^a
	5-CQA	3,5-diCQA	DHLc
Add 5-CQA
0.075 mM	96%	—	—
0.15 mM	97%	—	—
0.3 mM	94%	—	—
Add 3,5-diCQA
0.0075 mM	—	106%	—
0.03 mM	—	111%	—
0.075 mM	—	116%	—
Add DHLc
0.007 mM	—	—	106%
0.014 mM	—	—	103%
0.045 mM	—	—	122%

5-CQA: 5-mono-O-caffeoylquinic acid; 3,5-diCQA: 3,5-di-O-caffeoylquinic acid; DHLc: 11(S),13-dihydrolactucin.