Influence of Estrogen Receptor α Polymorphisms on Bone Density in Response to Habitual Exercise in Japanese Postmenopausal Women
Figure 2
The exercise effect on bone density scores classified by PvuII and XbaI RFLP genotypes and haplotypes. Values are expressed as mean ± SEM. The zero line is equal to the age-based mean value. Solid and open bars indicate the exercise and nonexercise groups, respectively. compared between the exercise and nonexercise groups in each ERα genotype and haplotype. (a) The mean score in the PP or pp genotype with exercise was significantly higher than that without exercise. (b) The Z score in the exercise group with xx genotypes was significantly higher than that of the nonexercise group. (c) The score in the exercise group with PPxx or ppxx genotype was significantly higher than that of the nonexercise group. The difference of habitual exercise in bone density was minimal in PpXx and Ppxx.
