Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis

<table>Effects of pioglitazone on ACE2 mRNA expression in insulin-sensitive tissues in rats fed a high-fat diet. In liver and adipose tissue, ACE2 mRNA expression was significantly greater in the HP group compared with the HFD group. In skeletal muscle, ACE2 mRNA expression did not differ between the HFD and HP groups. NC, normal control; HFD, high-fat diet; PC, pioglitazone control; HP, high-fat diet plus pioglitazone.</table>

The Scientific World Journal

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Figure 2: Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis 

Figure 2 | Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis 