Gastroprotective Activity of Violacein Isolated from Chromobacterium violaceum on Indomethacin-Induced Gastric Lesions in Rats: Investigation of Potential Mechanisms of Action
Figure 6
(a) Effect of violacein (40 mg/kg, orally) on proinflammatory cytokines (TNF-α, IL-1β, and IL-6) level; (b) anti-inflammatory cytokines (IL-4 and IL-10) level in indomethacin-induced ulcer. Values are mean ± SD (). compare vehicle + Indo with all the groups; compare Vio (40 mg) + Indo with SC560 (or) Celecoxib + Vio (40 mg) + Indo. Indo: indomethacin; Vio: violacein.
