Extract of Antrodia camphorata Exerts Neuroprotection against Embolic Stroke in Rats without Causing the Risk of Hemorrhagic Incidence
Figure 1
(a) Combination treatment of the extract of A. camphorata with aspirin against thromboembolic stroke in rats. Coronal sections of 2,3,5-triphenyltetrazolium- (TTC-) stained brains after thromboembolic occlusion-reperfusion rats were observed in a sham-operated group (sham), a group orally treated with an isovolumetric solvent (distilled water) for 60 days, followed by thromboembolic occlusion (MCAO group), groups orally treated with A. camphorata for 60 days alone, followed by thromboembolic occlusion, and groups orally treated with A. camphorata (0.25 and 0.75 g/kg/day) combined with aspirin (5 mg/kg/day) for 60 days, followed by thromboembolic occlusion as described in “Section 2.” The results are representative examples of three similar experiments; (b) densitometric analysis of the combination treatment of the extract of A. camphorata with aspirin against thromboembolic stroke in rats. Data are presented as the infarct volume for each animal in the group as well as the means ± S.E.M. (). compared to the sham-operated group, # and ## compared to the MCAO group.
